Impacts of Aging

 
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VIB.D.2

Lead Author(s): 

Jonathan S. Kirschner, MD, RMSK
Se Won Lee, MD

Supporting Author(s): 

Sylvia I. Watkins-Castillo, PhD

Incidence rates of ALS increase with age, peaking between 70 and 80 years. Amyotrophic lateral sclerosis is a fatal condition for most patients with mean life expectancy of about 3 years after diagnosis, although some patients live longer.

Although poliomyelitis (viral infection affecting nervous system) has been eradicated by vaccines developed in 1950's, polio survivors can suffer from post-polio syndrome for several decades (mean of 36 years) with gradual weakness, fatigue, and muscle wasting. A study published in 1994-1995 estimated there were about 1 million polio survivors in the US, with 443,000 reported having had paralytic polio. Considering 25% to 40% of polio survivors develop the post-polio syndrome, it is one of most prevalent motor neuron diseases in the elderly population.1

Edition: 

  • Fourth Edition

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