The National Institutes of Health (NIH) supports both basic and clinical investigation in osteoporosis. Within the NIH, the National Institute of Arthritis, Musculoskeletal, and Skin Diseases (NIAMS); the National Institute on Aging (NIA); the National Institute of Dental and Craniofacial Research (NIDCR); National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); and The National Institute of Child Health and Human Development (NICHD) all support osteoporosis-related research. NIAMS, the top institute for osteoporosis research, reported $72 million in osteoporosis research funding in fiscal year 2014, with an NIH-wide total of $141 million for osteoporosis-related projects.1 Additional research support is provided by other federal agencies including the Agency for Health Care Research and Quality (AHRQ), the Centers for Disease Control and Prevention (CDC), and the Veterans Administration Research program. The new Patient-Centered Outcomes Research Institute (PCORI) has also supported osteoporosis research. The top private and agency funds for osteoporosis include the American Society of Bone and Mineral Research and the American College of Rheumatology. Although numerous agencies fund osteoporosis research, the dollars available are limited in comparison to other conditions prevalent in older Americans. Additional research funding would assist in identifying treatments, management strategies, and factors that can minimize the burden associated with osteoporosis.